Drug Delivery Systems

Course: M.Pharmacy Code: 102T Branch: MPH Date: December 2023

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Total No. of Questions: 8] [Total No. of Printed Pages: 2 [2]
Roll No

MPH-102T

M.Pharmacy (PCI), I Semester

Examination, December 2023

Drug Delivery Systems

Time: Three Hours Maximum Marks : 70

Note:

  • i) Attempt any five questions.
  • ii) All questions carry equal marks.
1. a)

Define Polymers. Classify polymers on structural and functional basis with example.

b)

Explain tele-pharmacy and 3D printing of pharmaceuticals.

2.

Demonstrate the principle and functioning of:

i)

Feedback regulated Drug Delivery System.

ii)

pH activated drug delivery system.

iii)

Osmotic activated drug delivery system.

3. a)

Discuss the factors influencing buccal absorption of drug.

b)

Describe the modulation of GI transit time approaches to extend GI transit.

4.

Mention the role of the various dosage forms to overcome the effects of the barriers to ocular drug delivery.

5.

Write a brief note on the formulation approach of transdermal drug delivery systems.

6. a)

Describe in detail different strategies to formulate a stable protein and peptide drug formulations.

b)

Describe physical and chemical stability of proteins.

7. a)

Explain in detail mucosal and active transdermal methods of delivering vaccines through mucosa and skin.

b)

Explain single shot vaccines.

8. a)

What are biodegradable polymers? Explain various mechanism of polymer degradation from a drug delivery system.

b)

What are various evaluation methods of transdermal formulations?

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MPH-102T PTO