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F/2022/1949 Total Pages : 3 [2]

Final Year Pharmacy

PHARMACEUTICS-II

(201)

Time : Three Hours Maximum Marks : 80

Note :

  1. Attempt total six questions.
  2. Question No. 1 is compulsory.
  3. From the remaining questions attempt any five.
1.

Answer any five questions. 10

a) Fill in the blanks.

  1. Chloramphenicol is ______ solid.
  2. Calcium carbonate is ______ solid.

b) Give the metric equivalent of the following:

  1. One teaspoon full = ______ ml.
  2. One ounce = ______ g.

c) Translate the following Latin terms into English.

  1. Sumendus
  2. Nocte

d) Give the therapeutic dose of the following:

  1. Diazapam
  2. Paracetamol

e) State True/False

  1. Acacia is primary emulsifying agent.
  2. Contact lenses are usually made from polymethyl methacrylate.

f) Give two examples each of the following:

  1. Antioxidant
  2. Suspending agent
2.

Attempt any two questions : 14

a) Prepare 600 ml of a 1 in 100 solution of dextrose.

b)

  1. Calculate the real strength of 25° O.P. and 30° U.P.
  2. Find out the strength of 95% v/v alcohol in terms of proof spirit.

c) Prepare 05 suppositories each containing 2 g Iodoform. The displacement value of Iodoform is 4.0.

3.

Give reasons (Any four): 14

a) Tragacanth powder is used for the preparation of mixture containing indiffusible solid.

b) Alcohol is used for dispensing of powder prescription containing Boric acid and Iodine.

c) Liniment should not be applied to broken skin.

d) Oily vehicle is not used in the preparation of nasal drops.

e) White soft paraffin should not be used in the preparation of ophthalmic ointment.

4.

Differentiate any four of the following: 14

a) Tolerated and adjusted chemical incompatibility.

b) Micro emulsion and Simple emulsion.

c) Syrup and Elixir

d) Liniment and Lotion

e) Ointment and Paste

5.

Attempt any two: 14

a) Discuss following factors affecting dose and action of drugs.

  1. Body weight and size
  2. Route of administration
  3. Tachyphylaxis

b) Describe key ingredients, method of preparation and uses of dusting powder.

c) Explain the various adjuncts used in the formulation of mixtures.

[3]
6.

Attempt any two: 14

a) Describe method of preparation and uses of Cold cream.

b) Discuss various problems encountered during formulation by suspension. How will you remove it?

c) Classify briefly various emulsifying agent obtained from vegetable sources.

7.

Attempt any two: 14

a) What are Pyrogens? Give the reasons to remove from the parenteral preparation. Give the test for pyrogens.

b) Define the term "Dentifrice". What are the qualities of good dentifrice? Discuss in brief the formulation of dentifrices.

c) Classify Ophthalmic products. Give the ideal characteristics of these products.

8.

Write notes on any four of the following - 14

a) Vanishing creams

b) Tooth powder

c) Depilators (Hair removers)

d) Facial cosmetics

e) Packing, labelling and storage of Emulsions.