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F/2025/8102
Total Pages : 2
First Year Pharmacy
PHARMACEUTICAL CHEMISTRY
(ER20-12T)
Time : Three Hours
Maximum Marks : 80
Note :
i) Attempt any five questions.
ii) Each question carry equal marks.
1. a)
Write the structure and two uses of Aspirin and Paracetamol.
5
b)
Explain the structure and uses of Metformin, Acetylcholine, and Propranolol.
6
c)
What are Antacids? Classify them and write their uses and adverse effects.
5
2. a)
Draw the structure and write the uses of any four Antipsychotic agents.
6
b)
Classify NSAIDs and draw the structure of any two drugs from each class.
5
c)
Why is Paracetamol preferred over Aspirin in children? Justify your answer.
5
3. a)
Explain why Non-aqueous titration is preferred for certain drugs. Give two examples.
5
b)
Classify Antiretroviral drugs and draw their structure.
6
c)
What is the difference between Quinine and Quinidine?
5
4. a)
Calculate the molarity of a solution containing 8g NaOH in 500mL water.
5
b)
Write four properties of ideal disinfectants.
6
c)
What are the uses of Silver Nitrate and Potassium Permanganate?
5
5. a)
How do ACE inhibitors help in reducing blood pressure? Explain their mechanism of action.
5
b)
List four types of diuretics.
6
c)
Why are Potassium supplements given with Thiazides?
5
6. a)
Write a short note on anticonvulsant agents.
6
b)
List three side effects of Atropine.
5
c)
Write the structure and uses of Thiopental Sodium.
5
7. a)
Write the structure and uses of any two natural anticholinergic agents.
6
b)
Name two cholinergic drugs and their uses.
5
c)
What is the use and mechanism of Pralidoxime Chloride?
5
8. a)
Write the structure and mechanism of activation of alkylating agents. How they are used in cancer treatment?
6
b)
What is the mechanism of action of β-lactam antibiotics? Write the structure of Amoxicillin.
5
c)
Why is Folic Acid given with Methotrexate? Explain briefly.
5