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First Year Pharmacy
PHARMACEUTICAL CHEMISTRY
(ER20-12T)
Time : Three Hours
Maximum Marks : 80
Note :
i) This Paper is having three sections.
ii) All questions are compulsory.
iii) Attempt questions as per instructions given in each section.
Section-A
(Objective Type Questions)
Note : Answer all 20 questions (Multiple Choice Questions/Fill in the Blanks/One Word/One sentence Questions). Each question carries one mark.
20 × 1 = 20
In the limit test of chloride, the turbidity is due to the formation of
Which of the following anti-arrhythmic drugs is also a calcium channel blocker?
Which of the following is most potent diuretics?
Which of the following is a biguanide oral hypoglycemic agent?
Insulin preparations are classified on the basis of:
Which of the following antibiotic can be given to patient allergic to penicillin?
Tetracycline should not be taken with
Which of the following drug is used for the treatment of urinary tract infection?
Which of the following heterocyclic rings is the more basic?
Which of the following is a common antimalarial drug?
The impurities in substances such as metal are expressed in __________.
The cleaning action of dentifrices depends on __________.
___________ Heterocyclic ring is present in the structure of isoniazid?
Isosorbide dinitrate is used to treat __________.
The IUPAC name gives information about __________.
Carvedilol is used for treatment.
Acetaminophen is the chemical name, for which drug?
Which drug is a sulfonylurea derivative?
Which is the β-lactam antibiotics?
Which drug is used to treat fungal infections?
Section-B
(Short Answer Type Questions)
Note : Answer any ten questions out of eleven. Each question carries three marks.
10 × 3 = 30
Write the structure and uses of Acetylcholine.
What are oral hypoglycemic agents? Discuss the structure of any three drugs.
Write the structure and uses of Quinine Sulphate & Chloroquine.
Give the structure and uses of any two antipsychotic drugs.
Discuss the structure and synthesis of Isoniazid.
Describe the principle and procedure of precipitation titrations.
Write the principle and reactions involved in the limit test of iron.
Why antacids are given in combination always, explain with some marketed preparations.
What are haematinics? Examine the function of iron within the human body.
Give the structure, mechanism of action and uses of Frusemide.
Classify sedative and hypnotics with suitable examples.
Section-C
(Long Answer Type Questions)
Note : Answer any six questions out of seven. Each question carries five marks.
6 × 5 = 30
What are antiviral drugs. Classify them along with structure of each class.
What are the various measures to minimise impurities in pharmaceuticals? Why is quantification of impurities considered necessary in pharmaceuticals.
Classify anticancer drugs. Describe the medicinal chemistry of any two classes of anticancer agents with examples.
What are Anti-Depressants drugs. Classify them with along with their structure.
What are antacids. Write the method of preparation, chemical properties and pharmaceutical uses of sodium bicarbonate.
Classify analgesic and anti-inflammatory agents. Describe the structure of any two Nonsteroidal Anti-Inflammatory Drugs (NSAIDs).
Describe the chemistry, mechanism of action, and resistance of penicillin.