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F/2024/8102 Total Pages : 2 [2]

First Year Pharmacy

PHARMACEUTICAL CHEMISTRY

(ER20-12T)

Time : Three Hours Maximum Marks : 80

Note :

  1. Attempt any five questions.
  2. Each question carry equal marks.
1.
a) Define limit test. Write down principle and procedures of limit test of chloride. 8
b) Discuss briefly various sources of impurities in pharmaceutical substances. 4
c) Calculate the strength of 0.1 N.KmO4 solution. 4
2.
a) Write note on redox titrations. 6
b) Differentiate any two of the following: 4
  1. Primary and Secondary standard solution
  2. Molarity and Normality
  3. Equivalent weight and Molecular rate
c) Write a brief account of non-aqueous titrations. 6
3.
a) Define the following terms with two examples. 8
  1. Systemic Antacids
  2. Protectives
  3. Adsorbents
  4. Medicinal gases
b) Write down chemical name, chemical structure, storage, uses any two of the following. 8
  1. Thiopental sodium
  2. Diazepam
  3. Carbamazepine
  4. Dopamine
4.
a) Classify anti-arrhythmic drugs with suitable examples. 6
b) Give the structure, uses, storage and brand name of propranolol. 5
c) Give the full form of NSAIDs and give structure and uses of Aspirin. 5
5.
a) Give the two examples each of the following: 8
  1. High-efficiency diuretics
  2. Weak diuretics
  3. Narcotic analgesics
  4. Antianginal agents
b) Give the broad classification of Antihypertensive agents: Give the structure and uses of any two of them. 8
6.
a) Write a brief account of the sympathomimetic agents. 8
b) Give the properties, uses and marketed preparations of Insulin. 4
c) Discuss the structure, uses and storage of Metformin. 4
7.
a) Explain therapeutic uses of Narcotic analgesics. 5
b) Classify antifungal agents with suitable examples. 5
c) Give two examples each of the following: 6
  1. UTIs agents
  2. Antitubercular agents
  3. Antiviral agents
  4. Sulfonamides
8.
Write note any four of the following: 16
  1. Steps involved in Gravimetric analysis
  2. Structure and uses of Amoxicillin
  3. Mechanism of action of sulphonamides
  4. Structure and uses of Dapsone
  5. Classify Anti-neoplastic agents